The 53-year-old had not presented The Zoe Ball Breakfast Show since August 8. She told listeners their messages of support "meant the world".
And she paid tribute to fellow radio DJs Lauren Laverne and Jamie Theakston after they revealed they were battling cancer.
Zoe said: "I must say while we are sending some love our breakfast friends...Lauren Laverne, our mate at 6 Music is currently going through some cancer treatment.
"She's doing OK but I just want to send my love out to her."
Wanderer
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Blues make Marc as Guiu hits the jackpot
HAT-TRICK HERO IS QUICK TO SHATTER IRISH HOPES
Lane needs more rain
KEMPTON GROUND FEARS FOR JP'S TEAM
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Spike in admissions among young users
Profs win battle over smokers' wall
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There's NUN so good at crime fighting!
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Puffin pic secures prize for teenage twitcher Anwen
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'Blast' prank by soldier âreckless'
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Vegetarian piranha and DiCaprio snake among new species
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Anger over takeover of Titanic shipbuilder
Critics fear final assembly will move from Belfast to Spain
