For years, drug companies have enjoyed the freedom to charge high prices for their latest products. But when Sanofiand Amgen Inc. each marketed a powerful new cholesterol-lowering medicine, something surprising happened: High prices hurt sales. Sanofi’s experience has been especially painful. The French company spent more than five years developing Praluent with Regeneron Pharmaceuticals Inc. before its launch in 2015. But Praluent never caught on. Now Sanofi is cutting its losses, getting out of the U.S. market for the drug, and halting its heart disease research altogether in favor of more lucrative medicines for cancer and other diseases. “We’re proud of our past, but it shouldn’t dictate some poor investment decisions,” Paul Hudson, Sanofi’s new chief executive officer, told a group of investors last month. “We have to draw a line in the sand.”
What went wrong with Praluent? The drug is one of several cholesterol- lowering injections known as PCSK9 inhibitors. It does a better job than earlier drugs of reducing the risk of heart attacks and strokes for some people. Yet this class of new drugs has failed to reach more than a fraction of its intended market. Praluent’s disappointing sales are the result of insurance giants’ reluctance to pay for expensive new pharmaceuticals that treat chronic disease when far cheaper drugs can often get the job done.
Praluent’s disappointing performance shows how consolidation among insurers and pharmacybenefit managers—the middle men that handle prescription drug plans for employers and pension plans—has given them much more control over pricing and patient access to medicines.
Bu hikaye Bloomberg Businessweek dergisinin January 13, 2020 sayısından alınmıştır.
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Bu hikaye Bloomberg Businessweek dergisinin January 13, 2020 sayısından alınmıştır.
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