Nanoparticles are microscopic particles which are been widely used in various domain of science and technology.
With its small size, good solubility, customised surface properties and multifaceted uses nanoparticles have made a promising place in the current era of rapidly growing technology. Apart from its innumerable applications in industry, many nanoparticles have been considered vital in therapeutics and biomedical science. With the expanding health issues to mankind and potential peril of various life threatening diseases it has become a necessity to make diagnosis and treatment expeditious. Hence it is need of the hour to shed some light on the therapeutic uses of these nanoparticles such as in drug delivery.
Important Characteristics for nanoparticle drug delivery:
Particle size, determines the biological fate, its toxicity, and targeting ability. Moreover, they can influence drug loading, release, and stability of nanoparticles in biological membranes.
Surface properties:
Nanoparticles are recognised as foreign body by the immune system and are quickly opsonised by the immune cells. Thus it is important to minimise the opsonisation and hydrophobicity so that drug delivery is more efficient.To achieve this, nanoparticles are coated with hydrophilic copolymers like polyethylene glycol (PEG), polyethylene oxide, polyoxamer, poloxamine,
Drug loading capacity:
The drug loading capacity should be high and drug release depends on the solubility of the drug, desorption of the surface-bound or adsorbed drug.
هذه القصة مأخوذة من طبعة July-August 2018 من Scientific India.
ابدأ النسخة التجريبية المجانية من Magzter GOLD لمدة 7 أيام للوصول إلى آلاف القصص المتميزة المنسقة وأكثر من 9,000 مجلة وصحيفة.
بالفعل مشترك ? تسجيل الدخول
هذه القصة مأخوذة من طبعة July-August 2018 من Scientific India.
ابدأ النسخة التجريبية المجانية من Magzter GOLD لمدة 7 أيام للوصول إلى آلاف القصص المتميزة المنسقة وأكثر من 9,000 مجلة وصحيفة.
بالفعل مشترك? تسجيل الدخول
An insight into Chandipura virus in India
Recently lot of news regarding disease due to Chandipura virus has emerged in various newspapers/magazines. After reading the reports published it seems that thing is still brewing in the natures nest and it could affect mankind.
Why elephants never forget?
An elephant has a very large brain for its size and the 'temporal lobe' region responsible for memory is more developed with a greater number of folds - this results in powerful abilities to 'download' important survival data such as where to find food and water, and who is friend or foe.
Use of Algae for Wastewater Treatment Containing Heavy Metals
Wastewater treatment is a critical environmental issue particularly when it comes to the removal of heavy metals.
Nano priming Seeds: A Small Innovation Sparkling Big Advances in Germination
Nanopriming is an emerging agricultural technique where the seeds are treated with nanoparticles to improve their germination, growth, and overall performance.
Nobel Laureates in Physics 2024: Revolutionizing AlThe Physics Foundations Behind Machine Learning
This year's two Nobel Laureates in Physics have used tools from physics to develop methods that are the foundation of today's powerful machine learning.
Revolutionizing Biology: The 2024 Nobel Prize in Chemistry Celebrates Breakthroughs in Protein Design and Structure Prediction
The Nobel Prize in Chemistry 2024 is about proteins, life's ingenious chemical tools.
New findings on animal viruses with potential to infect humans
Scientists investigating animal viruses with potential to infect humans have identified a critical protein that could enable spillover of a family of organisms called arteriviruses.
Father-Daughter Team Decodes Mars' Alien Signal
There is no definitive answer to whether aliens exist, but there is a lot of work being done to find out:
Krishi Vigyan Kendras: Working for Farmer's Welfare
Krishi Vigyan Kendras (Farm Science Centres) are the District level institution serving as an agriculture knowledge resource & capacity development centre which plays indispensable role in front line extension regarding agriculture system in scientific way.
Sixth generation Computer: The future computing technology
We are in a transition towards a digital world, where everything will be dealt with in digital format.