Calorie restriction can extend lifespan in mammals, but the mechanism is not clear. Research by Prof Jean-Pierre Issa of Temple University suggests it works through epigenetics
What is epigenetics?
Our body has a single genome that we get from our father and mother. But we have more than 200 different cell and tissue types, all derived from a single blueprint, the genome. So how do you generate different tissues from one book or blueprint? The answer is a set of processes that we call ‘epigenetics’, because they work on top of genetics. They function like bookmarks that a cell uses to establish its cellular identity. They tell the heart, for example, which pages of the book it should use. We call them tags. Epigenetic tags can be molecules attached to DNA, or to the proteins around which DNA is wrapped, and just as you can sequence [read] the genome, you can sequence the entire ‘epigenome’.
How do these tags affect the ageing process?
هذه القصة مأخوذة من طبعة September - October 2018 من Very Interesting.
ابدأ النسخة التجريبية المجانية من Magzter GOLD لمدة 7 أيام للوصول إلى آلاف القصص المتميزة المنسقة وأكثر من 9,000 مجلة وصحيفة.
بالفعل مشترك ? تسجيل الدخول
هذه القصة مأخوذة من طبعة September - October 2018 من Very Interesting.
ابدأ النسخة التجريبية المجانية من Magzter GOLD لمدة 7 أيام للوصول إلى آلاف القصص المتميزة المنسقة وأكثر من 9,000 مجلة وصحيفة.
بالفعل مشترك? تسجيل الدخول
TAKE IT SLOW
Slow running is a fitness trend with some hard and fast science behind it
Physics, AI and music share a common thread. You just have to know where to look
Studying science can lead you in many directions and open doors to unexpected possibilities along the way
BED BUGS VS THE WORLD
When bloodthirsty bed bugs made headlines for infesting Paris Fashion Week in 2023, it shone a spotlight on a problem that's been making experts itch for decades: the arms race going on between bed bugs and humans
Kids are the key to understanding obesity. But we need more of their genes...
We can unravel the role that bodyweight plays in disease, but we need a bigger, more diverse, sample of genetic material to do so
COVID inquiry: What did we learn and what can we do better in future pandemics?
Masks, social distancing, lockdowns... how effective was the UK's response to the COVID-19 pandemic?
One hormone could be the key that unlocks a cure for morning sickness
The nausea and vomiting that, in extreme cases, can endanger mothers and babies might soon be just a memory
THE WORLD'S WEIRDEST CREATURES
Under the sea and upon the land, some animals look - to us - pretty strange...
WHEN MIND AND MACHINE COLLIDE
First, Elon Musk wanted to make electric cars ubiquitous, then he wanted to make space exploration a private enterprise. Now, with Neuralink, his newest venture, Musk hopes to merge humans and artificial intelligence. Turns out, it might not be such a crazy idea...
COME OUT OF YOUR SHELL
Social anxiety is more than just being shy. It's a phobia born out of our evolutionary past. But that raises a puzzling question: why do so many of us fear human interaction when we're supposed to be the most sociable species on the planet?
SPACE ODDITIES
Take a tour of the weirdest spots in the universe, where the 'normal' rules don't apply. Places that squeeze time, blow bubbles and even rain glass... sideways
