WATER IS USED THROUGHOUT THE pharmaceutical industry raw material, a process intermediate, a product ingredient and in the manufacturing of active pharma ingredients, intermediates and analytical reagents. Its wide use in many applications demands that manufacturers look very closely at regulatory requirements, specifications, purification methods, installation and validation.
Its usage as a diluent for reconstitution of products, vehicle during synthesis, ingredient as per composition, during the production of the finished product is also well established. Wide usage of water as a cleaning agent for rinsing vessels, equipment, primary packaging materials, etc.
The emphasis on the type of water used determines the quality of the water required and the guiding principle for the water processing system. Accordingly, usage of water can be broadly classified into the following categories:
1. Raw Water, for General purpose usage
2. Treated Water for drinking & Cleaning purposes
3. Purified water for Non-Aseptic formulations
4. Pyrogen-free WFI(water for injection) for Aseptic formulations
Therefore, special care and attention must be taken to ensure that the water used meets the required standard quality and that the purification process is designed suitably.
Water received from the corporation or drawn from the bore well is not used directly for any processes but is suitably treated before use and based on its classification. It is imperative to have the water tested & ensure it meets the specification in respective categories.
GENERAL PRINCIPLES FOR PHARMACEUTICAL WATER SYSTEMS
To ensure the appropriateness of water quality as per the usage, pharmaceutical water processing, storage, and distribution systems must be designed, installed, and qualified before use and essentially maintained following the stipulated guidelines.
Esta historia es de la edición September 2022 de Manufacturing Today.
Comience su prueba gratuita de Magzter GOLD de 7 días para acceder a miles de historias premium seleccionadas y a más de 9,000 revistas y periódicos.
Ya eres suscriptor ? Conectar
Esta historia es de la edición September 2022 de Manufacturing Today.
Comience su prueba gratuita de Magzter GOLD de 7 días para acceder a miles de historias premium seleccionadas y a más de 9,000 revistas y periódicos.
Ya eres suscriptor? Conectar
Innovate & integrate
The recently concluded roundtable on ‘Manufacturing Reimagined: A digital Leap with ServiceNow' focused on the role of digital transformation in manufacturing and supply chain management, emphasising the integration of digital technologies to enhance operational efficiency, sustainability, and business growth.
India's path to global semiconductor dominance
In conversation with Ashok Chandak, President IESA and Dr V Veerappan, Chairperson, IESA
Hydrogen: A catalyst for decarbonisation
Hydrogen is gaining momentum as a versatile solution with the potential to decarbonise various sectors. Exploring the current state of hydrogen, challenges and prospects that lie ahead.
Al's silent cyber attack
Take a sneak peek into the escalating threat of AI-driven cyber-attacks, along with the intricate challenges and imperative strategies in safeguarding against digital invasions.
Revolutionising energy efficiency
Effective electric motor rewinding practices are vital for enhancing energy efficiency and mitigating carbon emissions.
BEYOND TRACKS
From high-speed trains, metros, monorails, to turnkey systems, services, infrastructure, signalling and digital mobility, Olivier Loison, Managing Director of Alstom India delves into the company's century-old legacy and its stride towards the future.
Enhancing asset management with forefront RFID technology
Track, manage and monitor inventory of high-value assets using Zebra Integrated RFID technology to optimize workflow.
The role of robotics, automation & network integration
There is a symbiotic relationship between robotics, automation, and network technology. With the Internet of Things projected to exceed 25 billion devices, the integration of cutting-edge robots into interconnected systems is rapidly becoming a reality.
Pune Machine Tool Expo and FACTEQ 2024 to propel manufacturing progress in India
The four-day event featured around 230 exhibitors
UltraTech Cement's ₹800 crore investment
UltraTech's board greenlights capacity expansion at the Parli facility by 1.2 million tonnes