Since its introduction in 1964, Microcrystalline Cellulose (MCC) has revolutionized the pharmaceutical industry, serving as a vital ingredient in various drug formulations due to its unique properties like compressibility, flowability, and stability. Today, it is one of the most widely used excipients in pharmaceuticals, cosmetics, food, and other industries. Its invention has significantly contributed to enhancing the efficacy, safety, and overall quality of pharmaceutical products. Another remarkable feature of MCC is its bio-compatibility, making it safe for human consumption. The fact that it is derived from a natural and renewable source (cellulose from plant fibers) further adds to its appeal as a pharmaceutical excipient.
MCC is a crucial universal commodity with high demand and long term need for availability at almost all times. Being used in very high volumes in oral solid dosage forms, identifying, predicting and managing certain risk factors, which are mentioned below are a big challenge for procurement teams and also an essential part of a future oriented supply chain management strategy. Years in recent past have shown many sudden situations to us like once-in-a-century pandemic and geo-political situations affecting businesses like never before. In addition to these, here are few risk potentials working adversely to global pharmaceutical operations –
◆ Climate change/extreme weather conditions
◆ Natural calamities like Earthquakes/Floods/Droughts
◆ Epidemics
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