POPULAR heartburn be more mindful in monitoring medications have been patients who regularly take linked to deadly kidney the common acid reducers. failure!&nbsp;Most disturbingly, the damage caused by proton pump inhibitors (PPIs) occurs slowly and quietly until the condition is chronic, say researchers at Washington University School of Medicine in St. Louis and the Veterans Affairs St. Louis Health Care System. The shocking findings led experts to recommend doctors be more mindful in monitoring patients who regularly take the common acid reducers.&nbsp;&ldquo;The onset of acute kidney problems is not a reliable warning sign for clinicians to detect a decline in kidney function among patients taking proton pump inhibitors,&rdquo; said Dr. Ziyad Al-Aly, the study&rsquo;s senior author.&nbsp;&ldquo;Our results indicate kidney problems can develop silently and gradually over time, eroding kidney function and leading to long-term kidney damage or even renal failure. Patients should be cautioned to tell their doctors if they&rsquo;re taking PPIs and only use the drugs when necessary,&rdquo; explains Al-Aly.&nbsp;More than 15 million Americans have prescriptions for PPIs, but many more buy the drugs over-the-counter &mdash; and take them without a doctor&rsquo;s supervision.&nbsp;Researchers say 80 percent of study participants taking PPIs did not develop early stage organ problems after five years. But they warn more than half of chronic kidney damage and end-stage renal disease cases related to the drugs showed no early warning signs.&nbsp;Overall, the clinicians found people who took PPIs had more than a 30 percent higher risk of developing chronic kidney disease compared to those who took less effective acid-busting drugs known as H2 blockers.

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