The scale of the criminality would make Fayed, who died last year aged 94, one of Britain's most notorious sex offenders, and raises urgent questions about how he got away with his crimes.
Scotland Yard said five unnamed individuals were being investigated as suspected "facilitators" of the former owner of the luxury London store Harrods.
A huge review is also being undertaken into whether opportunities were missed in past police investigations and whether there are grounds to pursue past or current officers over corruption claims.
Last month, the Guardian reported claims that corrupt police officers had helped Fayed in persecuting members of his staff, including a young woman who allegedly rebuffed the Harrods owner's sexual advances.
The 111 cases of alleged abuse involving Fayed include 21 accusers who reported crimes to the police between 2005 and his death and 90 women who have come forward since the BBC aired a documentary into Fayed in September.
The Guardian understands that as soon as next week the Met will find out whether it faces an independent investigation into whether it bungled the claims of sexual violence against the Harrods boss.
The police watchdog, the Independent Office for Police Conduct, is considering whether its own investigators should investigate Britain's biggest force.
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