The Rams saw their League One charge hit a major stumbling block at Sixfields where Sam Hoskins scored the only goal of the game.
Derby also had defender Sonny Bradley sent off for a straight red card in stoppage time.
“It’s obviously frustrating and disappointing,” admitted Warne. “I didn’t think we were amazing, but I still felt we created enough chances to win the game. We had a bit of control in the first half, not a lot, but the goal we conceded was farcical and credit to Northampton, I congratulate them for the win.
“The chance they took was harder than the chances we missed and sometimes it’s determined on that and you need those moments to go your way but they didn’t today.
“We got more and more frustrated in the second half. There were a lot of stoppages and a lot of lying down and we just didn’t look very cohesive.
“Northampton literally got every player behind the ball apart from one, but we played too slow at times and we moved the ball side to side with no purpose.
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