Recently, four drugs being used experimentally for the treatment of COVID-19 have been disapproved by World Health Organization, declaring them to be ineffective. This declaration created a controversy as it was based on a mega-clinical trial called Solidarity Trial, conducted and organised by WHO in about 30 countries. However, claims have now cropped up that the socalled ‘ineffectiveness’ of the drugs was largely due to underlying genetic reasons related to the participants. The pharmaceutical companies which manufacture these drugs had raised such concerns, buthad failed to generate much interest or backing from the medical community, perhaps because it was WHO which had disapproved the drugs. Now, a paper published in Nature Genomic Medicine states that it was individual differences in terms of pharmacogenomics that made the drugs fail. Simply put, the reason for the failure of the drugs lies in how the genes and the molecular mechanisms of individual patients affected the drugs’ ability to defeat the ‘deathly hallow’- the COVID-causing coronavirus.
この記事は Future Medicine India の December 2020 版に掲載されています。
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この記事は Future Medicine India の December 2020 版に掲載されています。
7 日間の Magzter GOLD 無料トライアルを開始して、何千もの厳選されたプレミアム ストーリー、9,000 以上の雑誌や新聞にアクセスしてください。
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