If you’ve spent enough time in the gym lifting weights with great intensity, then you’re probably familiar with the muscle soreness that comes along with the territory.
Nonsteroidal anti-inflammatory drugs (NSAIDs), such as ibuprofen or aspirin, are commonly used to alleviate the stiffness and pain associated with muscle soreness so you can maintain your intensity level and workout schedule. However, while short-term NSAID use reduces muscle pain and stiffness, chronic use of NSAIDs to treat exercise-induced muscle soreness may impair the adaptive response to training, as evidence indicates that NSAID consumption impedes numerous processes involved in muscle growth and strength.1,2
DECREASED MUSCLE PROTEIN SYNTHESIS
Muscle growth from heavy resistance training greatly depends on the rate of protein synthesis within the muscle cell. Since inhibiting the cyclooxygenase-2 enzyme (COX-2) with NSAIDs reduces the production of prostaglandins that have been shown to regulate muscle protein synthesis3, a study by Trappe et al.4 investigated whether the well-known NSAID ibuprofen could also reduce the production of prostaglandins and more importantly, muscle protein synthesis after high-intensity resistance exercise. In this study, 24 healthy males consumed 1,200 milligrams of ibuprofen per day while performing 10 to 14 sets of leg extensions that involved eccentric repetitions at 120 percent of their one-repetition maximum. The results show that the normal increase in muscle protein synthesis that occurs within 24 hours after eccentric resistance training was decreased a great deal by ibuprofen consumption when compared to the placebo group. Moreover, ibuprofen consumption also caused a 77 percent decrease in the production of the prostaglandin PGF2-alpha. Taken together, these results demonstrate that NSAID consumption attenuates the post-exercise increase in muscle protein synthesis by blocking the COX2 production of PGF2-alpha, likely precluding muscle growth.
REDUCED MUSCLE GROWTH AND STRENGTH
この記事は Muscular Development の August 2019 版に掲載されています。
7 日間の Magzter GOLD 無料トライアルを開始して、何千もの厳選されたプレミアム ストーリー、9,000 以上の雑誌や新聞にアクセスしてください。
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この記事は Muscular Development の August 2019 版に掲載されています。
7 日間の Magzter GOLD 無料トライアルを開始して、何千もの厳選されたプレミアム ストーリー、9,000 以上の雑誌や新聞にアクセスしてください。
すでに購読者です? サインイン
Best Cardio for Fat Loss - High Intensity vs. Low Intensity
Low-intensity cardiovascular exercise is the most common way to reduce body fat, despite mounting scientific evidence showing this form of cardiovascular training may not burn body fat as effectively as high-intensity cardio. In addition, low-intensity cardio has also been shown to inhibit muscle growth¹2, making the use of this approach to enhance your physique even more questionable.
Are Unilateral Exercises More Effective Than Bilateral Exercises?
Bilateral exercises simultaneously use both limbs to lift the weight, so that the resistance is being shared between each limb.
THE AMAZING POWER OF JULIA DI POMPEO
Pro Figure Champ and Pro Powerlifter!
BRYAN JONES: THE LORD OF CLASSIC RETURNS!
It seems like a decade has passed since the pandemic began in 2020. That was a chaotic year for all of us. MD sent me to Atlanta to cover the Chicago Pro, because restrictions in Illinois made it impossible to hold Tim Gardner's annual extravaganza there. The athletes still showed up in force to compete, and the Classic Physique division alone featured 30 men. When they came out to be adjudicated, one man stood out in a flash as the one to beat. I had never heard of Bryan Jones until that point aside from a vague recollection that he'd won the USA a couple of years before. With his braided and colored hair piled on top of his head in a gathered bun with the ends appearing to be some type of bizarre plant, I dubbed him \"The Kai Greene of Classic.\" That didn't stick, thankfully, because Bryan \"Lord\" Jones is a unique athlete in his own right. I knew I was looking at a man who was going to make waves in that division. A few months later he did just that, placing fifth in his first Olympia appearance. But we only saw him twice more after that, at the Arnold Classic and once again at the Olympia at the end of 2021. Since then, Jones has been working hard to build the additional size needed to successfully transition to the Open category. I spoke with him about his brief but notable time in Classic, and how he plans to make a big splash in Open.
Andrew vs. Hunter: THE BATTLE FOR TEXAS!
A BATTLE IS BREWING
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Summer is in full swing, and for the vast majority of bodybuilders that don't compete, this is our showtime! All the many months of toiling away covered up while the sky was dark and gray and icy temperatures had you shivering have led to this. Last month we provided you with eight excellent tips to get ripped and ready, but let's take it a step further. This month, we enlisted the help of Classic Physique superstar and GAT Sport athlete Logan Franklin to come up with his best advice on how to make sure you have the most Classic-looking physique possible to show off on the beaches or at the pool. Here's what he has to say about the Classic look, areas of the physique to emphasize and how, and his best nutrition tips to make sure you turn plenty of heads this summer!
SUCCESS STORY: YANIV ZUR
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HOW MUCH REST IS BEST?
Getting enough rest after weight training is essential for optimal muscle growth and performance. Unfortunately, many get insufficient rest because they simply disregard the fact that weightlifting breaks down muscle tissue, creating the requirement for adequate rest to fully recuperate.
Get Peeled With Extra Virgin Olive Oil
As you know, pathologic fat accretion results in obesity. The medical community and pharmaceutical industry have been struggling to address this burgeoning condition in the Western culture - particularly in the United States. Obviously, individuals have also been struggling in their attempts to avoid or correct unsightly or unhealthy fat gain. Imagine the shame these professionals and people must feel when they realize they may have been ignoring a risk-free, health-promoting, inexpensive dietary ingredient that can enhance fat loss. Bodybuilders seek potent drugs or supplements to force the metabolism to strip body fat to low single-digit percentages, but failing to acknowledge the foundation of diet can sabotage even their extreme measures.
CREATINE: THE BEST FORMS
New products and formulations are introduced to the supplement market every day. However, it is very rare for a product or especially an ingredient to create noteworthy evolution in supplement performance. Arguably, the greatest leap up this axiomatic evolutionary ladder occurred with the advent of creatine supplements in the 1990s. Creatine has proven over and over to be \"the real deal\" in clinical research and broscience. It's a muscle-building, performance-enhancing supplement that nearly all athletes should use.
