Swedish researchers have isolated a molecule from breast milk with remarkable tumour-killing properties. Dubbed ‘HAMLET’, short for human alpha-lactalbumin, the substance is undergoing its first human trials.
How did you find HAMLET?
Catharina Svanborg We were looking for natural antibacterial molecules in body fluids. We threw some lung cancer cells into the test tube with human milk and noticed that the tumour cells died. We had to repeat it a few times before we could believe our eyes.
Was it just raw human milk?
No, it wasn’t, actually. Human milk is a source for all sorts of molecules – obviously, it’s a wonderful mix of molecular protection for babies. But we were using different fractions of it, because either you have antibodies, or you have small molecules, or you have sugars or lipids. Depending on which faction you’re using, you can get very different results. It turned out that one of these fractions was causing the tumours to die, but not whole milk as it comes out of the breast. It has to be treated a little to bring out the HAMLET molecule.
How exactly does it work?
この記事は Very Interesting の July/August 2020 版に掲載されています。
7 日間の Magzter GOLD 無料トライアルを開始して、何千もの厳選されたプレミアム ストーリー、9,000 以上の雑誌や新聞にアクセスしてください。
すでに購読者です ? サインイン
この記事は Very Interesting の July/August 2020 版に掲載されています。
7 日間の Magzter GOLD 無料トライアルを開始して、何千もの厳選されたプレミアム ストーリー、9,000 以上の雑誌や新聞にアクセスしてください。
すでに購読者です? サインイン
TAKE IT SLOW
Slow running is a fitness trend with some hard and fast science behind it
Physics, AI and music share a common thread. You just have to know where to look
Studying science can lead you in many directions and open doors to unexpected possibilities along the way
BED BUGS VS THE WORLD
When bloodthirsty bed bugs made headlines for infesting Paris Fashion Week in 2023, it shone a spotlight on a problem that's been making experts itch for decades: the arms race going on between bed bugs and humans
Kids are the key to understanding obesity. But we need more of their genes...
We can unravel the role that bodyweight plays in disease, but we need a bigger, more diverse, sample of genetic material to do so
COVID inquiry: What did we learn and what can we do better in future pandemics?
Masks, social distancing, lockdowns... how effective was the UK's response to the COVID-19 pandemic?
One hormone could be the key that unlocks a cure for morning sickness
The nausea and vomiting that, in extreme cases, can endanger mothers and babies might soon be just a memory
THE WORLD'S WEIRDEST CREATURES
Under the sea and upon the land, some animals look - to us - pretty strange...
WHEN MIND AND MACHINE COLLIDE
First, Elon Musk wanted to make electric cars ubiquitous, then he wanted to make space exploration a private enterprise. Now, with Neuralink, his newest venture, Musk hopes to merge humans and artificial intelligence. Turns out, it might not be such a crazy idea...
COME OUT OF YOUR SHELL
Social anxiety is more than just being shy. It's a phobia born out of our evolutionary past. But that raises a puzzling question: why do so many of us fear human interaction when we're supposed to be the most sociable species on the planet?
SPACE ODDITIES
Take a tour of the weirdest spots in the universe, where the 'normal' rules don't apply. Places that squeeze time, blow bubbles and even rain glass... sideways
