Cancer poses a significant challenge for the pharmaceutical industry, driving a constant search for improved oncology drugs. The industry has now put the spotlight on antibodydrug conjugates (ADCs), representing a promising frontier in targeted cancer treatment. 2023 was a big year for ADCs, marked by a total of 76 deals (by December 26, 2023) encompassing licensing agreements, collaborations, and acquisitions. Majority of the big pharma companies have either announced acquisitions or partnership with smaller biotech companies in this space, the latest entrant is Johnson & Johnson (J&J) which on January 8, 2024, made a significant move with a $2 billion acquisition of ADC developer Ambrx Biopharma, bolstering its ADC pipeline. Just a few weeks back, on December 26, 2023, J&J sealed a substantial $1.7 billion deal with South Korea's LegoChem Biosciences for the development and commercialisation of LCB84, a promising Trop2-directed ADC. The preclinical data for LCB84 highlighted a distinct safety and efficacy profile across various cancers, underlining the significance of these strategic advancements in the ADC landscape.
この記事は BioSpectrum Asia の BioSpectrum Asia Feb 2024 版に掲載されています。
7 日間の Magzter GOLD 無料トライアルを開始して、何千もの厳選されたプレミアム ストーリー、9,000 以上の雑誌や新聞にアクセスしてください。
すでに購読者です ? サインイン
この記事は BioSpectrum Asia の BioSpectrum Asia Feb 2024 版に掲載されています。
7 日間の Magzter GOLD 無料トライアルを開始して、何千もの厳選されたプレミアム ストーリー、9,000 以上の雑誌や新聞にアクセスしてください。
すでに購読者です? サインイン
Prof. Christian Wolfrum to join NTU as Deputy President and Provost
Nanyang Technological University, Singapore (NTU Singapore) has announced that Professor Christian Wolfrum, an eminent biomedical scientist, will be joining the University as the next Deputy President and Provost.
Japan suggests addition of PVA into drugs for strong antitumour activity
Treatment for more advanced and difficult-to-treat head and neck cancers can be improved with the addition of polyvinyl alcohol (PVA), the same ingredient used in children's glue.
"Demand for skilled medtech professionals in the Asia Pacific region is growing rapidly"
2024 saw Japanese medtech firm Olympus receiving approval for the company's first cloud-based AI endoscopy devices in the US and Europe, marking a significant milestone in Olympus' efforts to enhance clinical outcomes and operational efficiency in endoscopy, paving the way to launch its upcoming endoscopy solution, the “Intelligent Endoscopy Ecosystem”.
BeiGene names Giancarlo Benelli as Head of Europe biz
BeiGene, a Hong Kong-headquartered oncology company that intends to change its name to BeOne Medicines Ltd., has announced the appointment of Giancarlo Benelli as Senior Vice President and Head of Europe, effective January 1.
Korea develops innovative injectable adhesive hydrogel for bone regeneration
A research team from South Korea-based Pohang University of Science and Technology or POSTECH's Department of Chemical Engineering and Graduate School of Convergence Science and Technology, along with the Department of Chemical Engineering, has developed an innovative injectable adhesive hydrogel for bone regeneration.
When Clinical Trials Suffer From 'Complicated' Interactions
Diversity in culture, language, and data gathering methods will further increase the difficulty of clinical trials as they become more international, particularly with the growing number of sites being employed across China, Japan, South Korea, and India.
Dr Krishna M Ella receives prestigious INSA India fellowship
Dr Krishna Ella, a distinguished scientist, co-founder and Executive Chairman of Bharat Biotech International, has been recognised with the prestigious India Fellowship of the Indian National Science Academy (INSA) for the year 2025, for his contributions to new knowledge, discoveries, development of new vaccine technologies, noteworthy improvement in existing technologies.
Bruker launches infrared imaging microscope for pharma and life science research
US-based Bruker Corporation has announced the launch of the LUMOS II ILIM, a quantum cascade laser (QCL) based infrared (IR) imaging microscope.
Qiagen increases QIAcuity digital PCR high-order multiplexing capabilities
Qiagen has announced a significant increase in the powerful capabilities of its QIAcuity Digital PCR (dPCR) system with a more than two-fold increase in the number of targets that can be simultaneously analysed from a single biological sample.
Repligen unveils advanced UV-based Variable Pathlength Technology system for biopharma manufacturers
US-based Repligen Corporation has announced the commercial launch of its CTech SoloVPE PLUS System, the most advanced UV-based Variable Pathlength Technology system now available to biopharmaceutical manufacturers.
