But like many antivirals before it, scientists know that at some point, Paxlovid is likely to lose some efficacy due to drug resistance. Researchers working to stay ahead of such emerging threats have now identified a wholly new way to treat SARS-CoV-2 infections work that may have even broader implications.
In fact, a new study by the Tuschl laboratory introduces a proof-of-concept for a novel class of antivirals that would target a type of enzyme essential not just to SARS, but also many RNA viruses, including Ebola and dengue, as well as cytosolic- replicating DNA viruses, including Pox viruses. The findings may pave the way for a faster and more robust response to future pandemics. This work establishes cap methyl transferase enzymes as therapeutic targets and opens the door to many more antiviral developments against pathogens that until now we've had only limited tools to fight.
Denne historien er fra November - December 2024-utgaven av Scientific India.
Start din 7-dagers gratis prøveperiode på Magzter GOLD for å få tilgang til tusenvis av utvalgte premiumhistorier og 9000+ magasiner og aviser.
Allerede abonnent ? Logg på
Denne historien er fra November - December 2024-utgaven av Scientific India.
Start din 7-dagers gratis prøveperiode på Magzter GOLD for å få tilgang til tusenvis av utvalgte premiumhistorier og 9000+ magasiner og aviser.
Allerede abonnent? Logg på
Building world's 1st pyramid
In a preprint study published this summer, researchers proposed that ancient Egyptians built the world's first pyramid the 4,700-year-old Step Pyramid of Djoser, which sits on Egypt's Saqqara plateau using a \"modern hydraulic system\" powered by a long-gone branch of the Nile River.
Climate change arms the world, ovarian cancer pulls the trigger.It's time we disarm them both
Climate change, driven by human activities, leads to environmental changes such as rising temperatures, altered weather patterns, and increased pollution.
Climate Change Added 18 mph to Hurricane Wind Speeds over Past 5 Years
High ocean temperatures caused by global warming boosted maximum intensities for most storms between 2019 and 2023, as well as for every 2024 hurricane.
How Indian Vulture Decline Led to 500,000 Deaths in 5 Years
Once a common sight across India, vultures were abundant scavengers, often seen circling landfills in search of carcasses.
Understanding Monkeypox: Insights and Implications
Monkeypox, a viral zoonotic disease, has gained significant attention in recent years due to its re-emergence and sporadic outbreaks globally.
AI predicts that most of the world will see temperatures rise to 3°C much faster than previously expected
Three leading climate scientists have combined insights from 10 global climate models and, with the help of artificial intelligence (AI), conclude that regional warming thresholds are likely to be reached faster than previously estimated.
Infrared Radiation: A New Player In Mosquito Host-Seeking
The sound of mosquitoes is all around us when the sun sets and the air gets warm and sweltering.
Fish Oil May Benefit to Cure Alzheimer's, disorder: new findings
The benefits of fish and fish oil consumption are well-known in medical science as fish is considered a precious food resource that provides sufficient nutrition to humans.
A new class of antivirals could help prevent future pandemics
The arrival of Paxlovid in December 2021 marked another turning point in the COVID-19 pandemic an effective antiviral that has since successfully treated millions.
Turning carbon emissions into methane fuel
Chemists have developed a novel way to capture and convert carbon dioxide into methane, suggesting that future gas emissions could be converted into an alternative fuel using electricity from renewable sources. Carbon dioxide (CO2) is a greenhouse gas that accounts for a large part of Earth's warming climate, and is produced by power plants, factories and various forms of transportation.
