In this issue

THE TALK OF THE TOWN
Tyler Foggatt on the politics of cool;
Francis Ford Coppola, hotelier; a mag for mercenaries;
Hollywood meets the Vineyard; COVID déjà vu.

SHOUTS & MURMURS
Emily Zauzmer | Every Obituary’s First Paragraph

PROFILES
Molly Fischer | Be Her Guest | Ina Garten’s age of abundance.

BRAVE NEW WORLD DEPT
Dhruv Khullar | Drug of Choice | How A.I. learned to make medicine

THE HEM OF HIS GARMENT

An audience with the Pope.

10+ mins

SPREADING THE WEALTH

Why a young heiress asked fifty strangers to redistribute her fortune.

10+ mins

EVERY OBITUARY'S FIRST PARAGRAPH

Alfred T. Alfred, whose invention of the plastic fastener that affixes tags to clothing upended the tag industry and made him one of America’s youngest multimillionaires—until he lost his plastic fastener fortune in a 1993 game of badminton, as depicted in the Lifetime original movie “Bad Minton”— died on Saturday. He was eighty-one.

2 mins

BE HER GUEST

The plush ambience of Ina Garten's good fortune.

10+ mins

Drug of Choice - The natural world contains many billions of potential medications. The question is how to find the ones that work.

AI. is transforming the way medicines are made. Bacteria produce numerous molecules that could become medicines, but most of them aren’t easily identified or synthesized with the technology that exists today. A small percentage of them, however, can be constructed by following instructions in the bacteria’s DNA. Burian helped me search the sequence for genes that looked familiar enough to be understandable but unfamiliar enough to produce novel compounds. We settled on a string of DNA that coded for seven linked amino acids, the same number found in vancomycin. Then Burian introduced me to Robert Boer, a synthetic chemist who would help me conjure our drug candidate.

10+ mins

GREEN SLEEVES

“What I want to know,” the woman said to the therapist, “is why the voices always say mean, terrible things.

10+ mins

WILD THING

MJ Lenderman resists the smoothing, neutering effects of technology.

9 mins

LUCK OF THE DRAW

Nate Silver argues that poker can help us game our uncertain world.

10+ mins

DESPERATELY SEEKING

The supreme contradictions of Simone Weil.

10+ mins

DUTY DANCING

How Seamus Heaney wrote his way through a war.

10+ mins

Read all stories from The New Yorker

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The New Yorker is a weekly magazine that features journalism, commentary, criticism, essays, fiction, satire, cartoons, and poetry. It was founded in 1925 and is published by Condé Nast. The magazine is known for its in-depth reporting, its sharp and witty writing, and its iconic cartoons.

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